Objective To analyze the nursing effect of individualized nursing on patients with chronic urticariaMethods A total of 78 patients with chronic urticaria treated in the department of dermatology of our hospital from February 2020 to February 2021 were selected and divided into two groups according to the random number table method. 39 patients in the control group were given routine nursing service, and 39 patients in the study group were given individualized nursing. The nursing efficiency, the number of wind groups, symptom score, self-management ability score, disease control score and quality of life score were compared between the two groupsResults The total effective rate of nursing in the study group was higher than that in the control group, the difference was statistically significant (P＜0.05). The number of wind masses and symptom scores in the study group were lower than those in the control group, and the scores of self-management ability and disease control were higher than those in the control group, the difference was statistically significant (P＜0.05). The score of quality of life in the study group was significantly higher than that in the control group, the difference was statistically significant (P＜0.05)Conclusion The effect of individual nursing intervention for patients with chronic urticaria is significant, which can not only improve the nursing effect, but also control the development of the disease and improve the quality of life of patients, with high clinical value.