With the wide application of bone marrow mesenchymal stem cells in clinical practice, its defects seriously affect the repair effect. Adipose-derived stem cells (ADSCs) are derived from mesenchymal cells, which are similar to bone marrow mesenchymal stem cells and can effectively compensate for their defects in clinical treatment. Therefore, ADSCs have attracted widespread attention. Adipose-derived stem cells are of great significance in the field of medical beauty repair and reconstruction. This paper aims to analyze the research and application effect of adipose derived stem cells in the field of medical beauty repair and reconstruction.