Platelet rich plasma (PRP) is a platelet concentrate obtained after autologous whole blood centrifugation. It is rich in a variety of growth factors, which can promote cell proliferation, matrix remodeling and angiogenesis, thus playing an anti-inflammatoryrepair and tissue regeneration role. In recent years, it has been widely used in orthopedics, regenerative medicine, skin and so on. This article reviews the application and limitations of PRP in facial rejuvenation, scar repair, stria gravidarum and chloasma.