Objective To explore the application effect of oral implant repair in the treatment of dentition defect. Methods A total of 50 patients with dentition defect treated in our hospital from January 2020 to September 2021 were selected as the research objects. They were divided into control group and experimental group by random number table method, with 25 cases in each group. The control group was treated with conventional repair, and the experimental group was treated with oral implant repair. The repair effect, language ability after repair, chewing function, stability, tooth comfort and incidence of adverse reactions were compared between the two groups. Results The total effective rate of treatment in the experimental group was higher than that in the control group, and the difference was statistically significant (P<0.05). The scores of language ability, chewing function, stability and tooth comfort in the experimental group were higher than those in the control group, and the differences were statistically significant (P<0.05). The incidence of adverse reactions in the experimental group was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion Oral implant repair can improve the clinical effect of patients with dentition defect, and the incidence of adverse reactions is lower than that of conventional repair.