Objective To explore the clinical effect and cosmetic effect of minimally invasive resection in the treatment of accessory breast tumors. Methods From September 2021 to September 2022, 60 patients with accessory breast tumors admitted to our hospital were selected as the research objects. According to the random number table, they were divided into observation group and control group, with 30 cases in each group. The control group was treated with traditional accessory breast tumor resection, and the observation group was treated with minimally invasive resection. The satisfaction, surgical indicators, complications and pain degree of the two groups were compared. Results The total satisfaction rate of the observation group was 93.33%, which was higher than 66.67% of the control group (P0.05). The operation time and healing time of the observation group were shorter than those of the control group (P