Objective To explore the application effect of high quality nursing intervention in lattice laser treatment of acne scar patients. Methods From September 2020 to September 2021,100 patients with acne scar who underwent fractional laser treatment in our hospital were selected as the research objects. They were randomly divided into control group and observation group, with 50 cases in each group. The control group was given routine nursing, and the observation group was given high quality nursing intervention on the basis of the control group. The acne scar condition, nursing satisfaction and complications were compared between the two groups. Results The acne scar score of the observation group was lower than that of the control group, and the nursing satisfaction score was higher than that of the control group, the difference was statistically significant (P