Objective To explore the application effect of LED light nursing in wound repair after fractional laser treatment of acne depressed scar. Methods Thirty patients with acne scars admitted to the medical cosmetology department of our hospital from January to December 2021 were randomly divided into control group and intervention group, with 15 cases in each group. Both groups received fractional laser treatment. The control group received routine nursing, while the intervention group received LED light nursing on the basis of the control group. The pain degree, pruritus index, decrustation days and VISIA skin detector score were compared between the two groups. Results The pain score of the intervention group was lower than that of the control group, and the difference was statistically significant (P