Objective To evaluate the clinical efficacy of modified frontalis muscle suspension with polytetrafluoroethylene material (e-PTFE) in the treatment of congenital blepharoptosis in young children. Methods From January 2019 to June 2022, 42 children (52 eyes) with congenital ptosis who underwent e-PTFE modified frontal muscle suspension in our hospital were selected as the research objects. Forty-two patients were followed up at 1, 3 and 6 months after operation. The upper eyelid-to-pupil margin reflex distance (MRD), palpebral fissure height, eyelid closure time, cosmetic effect and complications were compared before and after operation. Results The MRD and palpebral fissure height at 1, 3 and 6 months after operation were higher than those before, THE difference was statistically significant (P<0.05). The average eyelid closure time was (2.36±0.88) months. The cosmetic effect scores at 1, 3 and 6 months after operation were (8.12±0.52) scores, (7.78±0.60) scores and (7.65±0.42) scores, respectively; with the prolongation of time, the score decreased slightly, but the difference was not statistically significant (F=1.675, P>0.05). The total incidence of complications was 3.84%. Conclusion e-PTFE modified frontalis muscle suspension combined with individualized double eyelid plasty for the treatment of congenital blepharoptosis in young children has good results.