Objective To explore the pathway of hospital information construction under the new public health management. Methods Sixty patients who underwent the hospital information construction pathway from January 2022 to January 2023 in our hospital were selected as the observation group, while 60 patients who underwent routine management but did not undergo the information construction pathway from December 2020 to December 2021 were selected as the control group. The management quality scores, patient satisfaction and incidence of adverse events were compared between the two groups. Results The management quality score of each link and patient satisfaction in the observation group were higher than those in the control group, and the incidence of adverse events was lower than that in the control group, the diferences were statistically signifcant (P<0.05). Conclusion The application value of hospital information construction pathway under the new public health management is high, which can not only improve the management quality of each link, but also reduce the occurrence of adverse events, promote patients to be more satisfed with management, and have higher clinical application value.