Objective To compare the clinical effects of minimally invasive extraction and hammer chisel split crown in the treatment of patients with mandibular low impacted wisdom tooth. Methods A total of 84 patients with mandibular low impacted wisdom tooth admitted to our hospital from January 2020 to December 2021 were selected as the research objects. According to different treatment methods, they were divided into control group and study group, with 42 patients in each group. The control group was treated with hammer chisel splitting crown method, and the study group was treated with minimally invasive tooth extraction method. The complications, operation time and pain degree of the two groups were compared. Results The incidence of intraoperative and postoperative complications in the study group was lower than that in the control group, and the difference was statistically significant (P<0.05). The operation time of the study group was shorter than that of the control group, and the difference was statistically significant (P<0.05). The VAS scores of the study group after 1, 3 and 5 days of treatment were lower than those of the control group, and the differences were statistically significant (P<0.05). Conclusion The effect of minimally invasive extraction for patients with mandibular low impacted wisdom tooth is better than that of hammer chisel split crown method, which can effectively reduce the risk of intraoperative and postoperative complications, reduce the pain degree of patients, improve the prognosis and promote the rapid recovery of patients.