+高级检索
首页 > 过刊浏览>2023年第32卷第8期 >176-179. DOI:10.3969/j.issn.1004-4949.2023.08.048
PDF HTML阅读 XML下载 导出引用 引用提醒
超分子水杨酸在皮肤病中的应用研究进展
作者:
作者简介:

成春梅（1997.5-），女，云南昭通人，硕士研究生，主要从事损容性皮肤病研究

通讯作者:

马琼（1978.5-），女，云南大理人，副教授，硕士生导师，主要从事损容性皮肤病研究

中图分类号:

Q946.82+8.3

基金项目:

1.云南省教育厅科学研究基金项目（编号：2023J0891）；2.云南省教育厅科学研究基金项目（编号：2023Y0979）


Research Progress on the Application of Supramolecular Salicylic Acid in Skin Diseases
Author:
  • 摘要
    • | |
  • 访问统计
    • |
  • 参考文献 [36]
    • |
  • 相似文献 [20]
    • | | |
  • 文章评论
    摘要:

    超分子水杨酸作为水杨酸的一种控缓释剂型，对皮肤具有抗炎、抗菌、双向调节角质等作用， 因此近年来广泛应用于皮肤病的临床治疗中。本文详细介绍了超分子水杨酸的作用机理，并结合相关文献 报道综述超分子水杨酸在皮肤科的应用，包括痤疮、玫瑰痤疮、黄褐斑、炎症后色素沉着及其他皮肤病， 以期为超分子水杨酸的临床应用提供参考。

    Abstract:

    Supramolecular salicylic acid, as a controlled and sustained-release formulation of salicylic acid, has antiinflammatory, antibacterial, and bidirectional cutin regulation effects on the skin, so it has been widely used in the clinical treatment of skin diseases in recent years. This paper introduces the mechanism of supramolecular salicylic acid in detail, and reviews the application of supramolecular salicylic acid in dermatology, including acne, acne rosacea, chloasma, postinflammatory melanosis and other skin diseases, so as to provide reference for the clinical application of supramolecular salicylic acid.

    参考文献
    [1] Arif T.Salicylic acid as a peeling agent:a comprehensive review[J].Clinical,Cosmetic and Investigational Dermatology,2015,8:455-461.
    [2] Klinge SA,Sawyer GA.Effectiveness and Safety of Topical versus Oral Nonsteroidal Anti-inflammatory Drugs: A Comprehensive Review[J].The Physician and Sportsmedici ne,2013,41(2):64–74.
    [3] Housby JN,Cahill CM,Chu B,et al.Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce HSP70 in human monocytes[J]. Cytokine,1999,11(5):347-358.
    [4] 郑梦丹,刘莉莉,李娴静,等.基于水杨酸和硫脲碳纳 米点的制备及其抗炎作用研究[J].口腔颌面外科杂 志,2022,32(2):77-84.
    [5] 李敬,韩凤娴,石晶,等.火针联合超分子水杨酸治疗面部 寻常痤疮的疗效对比研究[J].中国中西医结合皮肤性病 学杂志,2022,21(4):333-336.
    [6] Imayama S,Ueda S,Isoda M.Histologic Changes in the Skin of Hairless Mice Following Peeling With Salicylic Acid[J].Archives of Dermatology,2000,136(11):1390-1395.
    [7] Saint-Léger D,Lévêque J-L,Verschoore M.The use of hydroxy acids on the skin:characteristics of C 8 -lipohydroxy acid[J].Journal of Cosmetic Dermatology,2007,6(1):59-65.
    [8] Dainichi T,Ueda S,Furue M,et al.By the grace of peeling: the brace function of the stratum corneum in the protection from photo-induced keratinocyte carcinogenesis[J]. Archives of Dermatological Research,2008,300(S1):31-38.
    [9] Lu J,Cong T,Wen X,et al.Salicylic acid treats acne vulgaris ﹣179﹣ by suppressing AMPK/SREBP 1 pathway in sebocytes[J]. Experimental Dermatology,2019,28(7):786-794.
    [10] Marczyk B,Mucha P,Budzisz E,et al.Comparative study of the effect of 50% pyruvic and 30% salicylic peels on the skin lipid film in patients with acne vulgaris[J].Journal of Cosmetic Dermatology,2014,13(1):15-21.
    [11] Sgontzou T,Armyra K,Kouris A,et al.Repeated salicylic acid peels for the treatment of hyperplastic sebaceous glands in hypohidrotic ectodermal dysplasia[J].Journal of Cosmetic and Laser Therapy,2014,16(6):293-295.
    [12] 姚露,彭红霞,周文瑞,等.超分子水杨酸联合粉刺挤压治 疗寻常型痤疮疗效观察[J].皮肤病与性病,2020,42(3):377- 379.
    [13] 胡南,肖志平,温云鹏,等.超分子水杨酸联合胶原贴敷料治 疗轻中度痤疮临床观察[J].临床皮肤科杂志,2018,47(7):464- 467.
    [14] Tan JK,Bhate K.A global perspective on the epidemiology of acne[J].Br J Dermatol,2015,172 (Suppl)1:3-12.
    [15] 鲁亚青,段亚琼,范琳婵,等.超分子水杨酸治疗痤疮的效 果及对皮肤屏障的影响[J].中国美容医学,2020,29(3):9-11.
    [16] Dayal S,Amrani A,Sahu P,et al.Jessner’s solution vs 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris[J].Journal of Cosmetic Dermatology,2017,16(1):43-51.
    [17] Dayal S,Singh S,Sahu P.Efficacy and Safety of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild-to-Moderate Acne Vulgaris: A Comparative Study[J]. Dermatol Pract Concept,2021,11(3):e2021063.
    [18] 夏栩琼,徐慧,陆雯丽,等.30%超分子水杨酸治疗寻常痤 疮的疗效观察[J].中国皮肤性病学杂志,2019,33(5):616- 619.
    [19] Zheng Y,Yin S,Xia Y,et al.Efficacy and safety of 2% supramolecular salicylic acid compared with 5% benzoyl peroxide/0.1% adapalene in the acne treatment:a randomized,split-face,open-label,single-center study[J]. Cutaneous and Ocular Toxicology,2019,38(1):48-54.
    [20] 祝霞,孙丽玲.红蓝光、强脉冲光联合新型超分子水杨酸 治疗寻常性痤疮疗效观察[J].中国美容医学,2016,25(6):65- 67.
    [21] 周静芳,王艳玲,张维娜,等.强脉冲光、红蓝光联合超分 子水杨酸对寻常痤疮患者免疫功能及炎性介质的影响 [J].中国美容医学,2021,30(3):44-47.
    [22] 贾煜,顾汉江,刘亚乐,等.小剂量异维A酸联合2%超 分子水杨酸治疗中重度痤疮疗效观察[J].中国美容医 学,2020,29(5):16-19.
    [23] 李迪,刘晶,夏君,等.新型超分子水杨酸联合米诺环素胶 囊与克林霉素磷酸酯凝胶治疗寻常性痤疮疗效观察[J]. 中国美容医学,2019,28(6):51-55.
    [24] 曹雅晶,仲少敏,苑辰,等.外用水杨酸在玫瑰痤疮治疗中 的应用效果研究[J].中国美容医学,2019,28(4):31-35.
    [25] 侯燕,穆延芳,韩金斗.超分子水杨酸辅助治疗玫瑰痤疮 疗效观察[J].中国美容医学,2021,30(2):22-25.
    [26] 周星,姚新宇,栗玉珍.超分子水杨酸联合米诺环素治疗 玫瑰痤疮疗效观察[J].中国美容医学,2020,29(9):14–17.
    [27] 薛竞,王倩,周夕湲,等.超分子水杨酸治疗毛周角化病临 床疗效研究[J].中国美容医学,2019,28(7):18-20.
    [28] Wang L,Li X,Wen X,et al.Retrospective analysis of 19 papulopustular rosacea cases treated with oral minocycline and supramolecular salicylic acid 30% chemical peels[J].Experimental and Therapeutic Medicine,2020,20(2):1048-1052.
    [29] 杨蓉娅,蒋献.化学剥脱术临床应用专家共识[J].实用皮 肤病学杂志,2019,12(5):257-262.
    [30] Ejaz A,Raza N,Iftikhar N,et al.Comparison of 30% salicylic acid with Jessner’s solution for superficial chemical peeling in epidermal melasma[J].Coll Physicians Surg Pak,2008,18(4):205-208.
    [31] 王洪燕.水杨酸换肤结合点阵激光在女性黄褐斑面部美 容中的应用[J].中国美容医学,2021,30(11):69-74.
    [32] Joshi SS,Boone SL,Alam M,et al.Effectiveness, Safety, and Effect on Quality of Life of Topical Salicylic Acid Peels for Treatment of Postinflammatory Hyperpigmentation in Dark Skin[J].Dermatol Surg,2009,35(4):638-644.
    [33] Bari AU,Iqbal Z,Rahman SB.Tolerance and safety of superficial chemical peeling with salicylic acid in various facial dermatoses[J].Indian J Dermatol Venereol Leprol,2005,71(2):87-90.
    [34] 邓映,杜宇,杨洪秋,等.30%超分子水杨酸治疗痤疮炎症 后色素沉着疗效观察[J].中国美容医学,2021,30(10):78- 81.
    [35] Abadjieva TI.Treatment of androgenetic alopecia i n f e m a l e s i n r e p r o d u c t i v e a g e w i t h t o p i c a l estradiolbenzoate,prednisolon and salicylic acid[J].Folia Med (Plovdiv),2000,42(3):26-29.
    [36] Anzai A,Pereira AF,Malaquias KR,et al.Efficacy and safety of a new formulation kit(shampoo+lotion)containing anti-inflammatory and antioxidant agents to treat hair loss[J].Dermatol Ther,2020,33(3):e13293.
    引证文献
    网友评论
    网友评论
    分享到微博
    发 布
引用本文

成春梅,刘婷婷,黄 玲,等.超分子水杨酸在皮肤病中的应用研究进展[J].医学美学美容,2023,32(8):176-179.

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 在线发布日期: 2023-07-24
您是第83721 位访问者
地址：陕西省西安市新城区新科路1号东兴科技大厦12层
电话：029-83237788
运营单位：陕西医美文化传媒有限责任公司

《医学美学美容》官方微信

医学美学美容 ® 2025 版权所有 ICP：陕ICP备16007981号