With the continuous development of social economy, people pay more and more attention to their own image. Many patients with soft tissue depression on the body surface will choose to use medical and aesthetic methods for filling. As a biodegradable polymer material, poly-L-lactic acid is not only suitable for the filling treatment of facial areas, but also can be used in the repair of acne scars, ankle scars, hip scars and hand back scars. Therefore, this article will review the latest research on poly L-lactic acid in the repair of soft tissue on the body surface, in order to provide some reference value for related research.