优化脉冲光联合 1064 nm 超皮秒激光治疗黄褐斑合并褐青色痣的效果
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张传香(1972.7-),女,江苏南京人,本科,副主任医师,主要从事皮肤光声电、美塑等联和诊治相关工作

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R758.4+2

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Effect of Optimal Pulse Technology Combined with 1064 nm Ultra-picosecond Laser in the Treatment of Chloasma with Nevus Fusco
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    摘要:

    目的 探讨应用优化脉冲光与1064 nm超皮秒激光治疗黄褐斑合并褐青色痣的效果。方法 选取 2021年3月-2022年3月我院收治的60例黄褐斑合并褐青色痣患者作为研究对象,采取随机数字表法分为观 察组与对照组,各30例。观察组接受优化脉冲光联合1064 nm超皮秒激光治疗,对照组接受1064 nm超皮秒 激光治疗,比较两组临床疗效、复发率、VISIA皮肤图像分析结果以及血清氧化应激指标。结果 观察组治 疗总有效率为96.67%,高于对照组的80.00%(P<0.05);观察组随访12个月复发率为3.33%,低于对照 组的20.00%(P<0.05);观察组治疗后色斑、毛孔、皱纹、纹理、紫质评分均低于对照组(P<0.05); 观察组疗程结束后血清超氧化物歧化酶检测结果高于对照组,丙二醛、过氧化脂质检测结果均低于对照 组(P<0.05)。结论 优化脉冲光与1064 nm超皮秒激光治疗黄褐斑合并褐青色痣的效果确切,复发率低, 可有效改善患者面部皮肤情况,值得临床应用。

    Abstract:

    Objective To investigate the effect of optimal pulse technology combined with 1064 nm ultra-picosecond laser in the treatment of chloasma with nevus fusco. Methods From March 2021 to March 2022, 60 patients with chloasma and nevus fusco admitted to our hospital were selected as the research objects. They were divided into observation group and control group by random number table method, with 30 patients in each group. The observation group was treated with optimal pulsed light combined with 1064 nm ultra-picosecond laser, and the control group was treated with 1064 nm picosecond laser. The clinical efficacy, recurrence rate, VISIA skin image analysis results and serum oxidative stress indexes were compared between the two groups. Results The total effective rate of treatment in the observation group was 96.67%, which was higher than 80.00% in the control group (P<0.05). The recurrence rate of the observation group was 3.33% after 12 months of follow-up, which was lower than 20.00% of the control group (P<0.05). After treatment, the scores of color spots, pores, wrinkles, texture and purple matter in the observation group were lower than those in the control group (P<0.05). After the treatment, the serum superoxide dismutase test results of the observation group were higher than those of the control group, and the malondialdehyde and lipid peroxide test results were lower than those of the control group (P<0.05). Conclusion Optimal pulsed light and 1064 nm ultra-picosecond laser are effective in the treatment of chloasma with nevus fusco, and the recurrence rate is low. Meanwhile, it can effectively improve the facial skin of patients and is worthy of clinical application.

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张传香.优化脉冲光联合 1064 nm 超皮秒激光治疗黄褐斑合并褐青色痣的效果[J].医学美学美容,2023,32(13):56-59.

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  • 在线发布日期: 2023-09-26
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