In order to analyze the improvement effect of poly-L-lactic acid microneedle introduction on skin quality, this study selected 12 patients who underwent skin quality improvement intervention in our hospital from January to June 2022 as the research object, and used poly-L-lactic acid microneedles for intervention. The results showed that the overall improvement effect of facial skin quality was better in 6 patients who received facial skin quality improvement after treatment, and the brightening effect was very ideal. The score of brown spot area after treatment was (76.58±23.71) scores, which was lower than (110.21±24.36) scores before treatment, and the difference was statistically significant (P