阿维 A 胶囊口服联合外用他扎罗汀倍他米松乳膏治疗斑块型银屑病的临床效果
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范毅鹏(1975.12-),男,广西平南县人,本科,主治医师,主要从事皮肤疾病临床诊疗与皮肤美容工作

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R758.63

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Clinical Effect of Oral Acitretin Capsules Combined with Topical Tazarotene and Betamethasone Dipropionate Cream in Treatment of Plaque Psoriasis
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    摘要:

    目的 分析外用他扎罗汀倍他米松乳膏与口服阿维A胶囊在治疗斑块型银屑病中的应用效果。方 法 选取2020年8月-2022年8月我院收治的172例斑块型银屑病患者为研究对象,随机分对照组与试验组, 各86例。对照组给予阿维A胶囊口服治疗,试验组给予阿维A胶囊口服联合外用他扎罗汀倍他米松乳膏治 疗,比较两组临床疗效、皮肤病生活质量、皮损情况及不良反应发生情况。结果 试验组治疗总有效率为 97.67%,高于对照组的87.21%(P<0.05);试验组治疗后PASI、DLQI评分低于对照组(P<0.05);两组 不良反应发生率比较,差异无统计学意义(P>0.05)。结论 斑块型银屑病治疗中,口服阿维A胶囊联合外 用他扎罗汀倍他米松乳膏治疗的效果确切,可有效改善患者的生活质量和皮损情况,且不增加不良反应。

    Abstract:

    Objective To analyze the application effect of topical tazarotene and betamethasone dipropionate cream and oral acitretin capsules in the treatment of plaque psoriasis. Methods A total of 172 patients with plaque psoriasis admitted to our hospital from August 2020 to August 2022 were randomly divided into control group and experimental group, with 86 patients in each group. The control group was treated with acitretin capsules orally, and the experimental group was treated with acitretin capsules orally combined with tazarotene and betamethasone dipropionate cream. The clinical efficacy, quality of life of skin diseases, skin lesions and adverse reactions were compared between the two groups. Results The total effective rate of treatment in the experimental group was 97.67%, which was higher than 87.21% in the control group (P0.05). Conclusion In the treatment of plaque psoriasis, oral acitretin capsules and topical tazarotene and betamethasone dipropionate cream have a definite therapeutic effect, which can effectively improve the quality of life and skin lesions of patients without increasing adverse reactions.

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范毅鹏.阿维 A 胶囊口服联合外用他扎罗汀倍他米松乳膏治疗斑块型银屑病的临床效果[J].医学美学美容,2023,32(13):84-86.

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  • 在线发布日期: 2023-09-26
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