Objective To explore the application effect of psychological nursing in patients undergoing breast plastic surgery. Methods Sixty patients who underwent breast plastic surgery in our hospital from January 2022 to January 2023 were selected as the subjects of this study. They were divided into control group and study group by random number table method, with 30 patients in each group. The control group was given routine nursing, and the study group was given psychological nursing on the basis of the control group. The adverse emotions, nursing satisfaction and quality of life were compared between the two groups. Results The SAS score and SDS score of the study group after nursing were lower than those of the control group, and the difference was statistically significant (P