Objective To explore the application value of individual oral nursing in patients with oral and maxillofacial diseases. Methods A total of 80 patients with oral and maxillofacial diseases admitted to our hospital from January to December 2022 were randomly divided into control group and observation group, with 40 patients in each group. The control group received routine nursing, and the observation group implemented individual oral nursing on the basis of the control group. The clinical efficacy, treatment compliance, psychological status score, nursing satisfaction and complication rate were compared between the two groups. Results The total effective rate of treatment in the observation group was 95.00%, which was higher than 67.50% in the control group, and the difference was statistically significant (P