Objective To evaluate the effect of nano-composite resin materials in aesthetic restoration of anterior teeth. Methods A total of 80 patients with aesthetic restoration of anterior teeth admitted to our hospital from June 2020 to June 2022 were selected as the research objects. They were divided into control group and observation group by random number table method, with 40 patients in each group. The control group was repaired with light-cured composite resin materials, and the observation group was repaired with nano-composite resin materials. The repair effect, periodontal status before and after repair, and postoperative pain were compared between the two groups. Results The GI and SBI of the observation group after repair were lower than those of the control group, and the differences were statistically significant (P