Objective To explore the effect of oral repair in the treatment of elderly patients with oral diseases. Methods A total of 70 elderly patients with oral diseases admitted to our hospital from February 2020 to February 2023 were selected as the research objects. They were divided into experimental group and control group by random number table method, with 35 patients in each group. The experimental group received oral repair treatment, and the control group received basic oral treatment. The periodontal improvement, quality of life, disappearance time of clinical symptoms, incidence of adverse reactions and treatment satisfaction were compared between the two groups. Results After treatment, the bleeding index, plaque index and gingival index of the experimental group were lower than those of the control group, and the difference was statistically significant (P