赵玲（1991.1-），女，四川成都人，本科，住院医师，主要从事皮肤与性病学方面研究
R758.73+
目的 分析强脉冲光联合他克莫司软膏治疗玫瑰痤疮的临床效果。方法 选择2021年10月-2022年 12月于我院就诊的105例玫瑰痤疮患者为研究对象，根据随机数字表法分为A组、B组、C组，每组35例。 A组给予强脉冲光治疗，B组给予他克莫司软膏治疗，C组给予强脉冲光联合他克莫司软膏治疗，比较三 组临床疗效、皮肤屏障功能及不良反应发生情况。结果 C组治疗总有效率高于A组、B组（P＜0.05）； 三组治疗2个月后角质层含水量均高于治疗前，EI、TEWL均低于治疗前（P＜0.05）；C组治疗2个月后 角质层含水量高于A组、B组，EI、TEWL低于A组、B组（P＜0.05）；C组不良反应发生率低于A组、B 组（P＜0.05）。结论 强脉冲光联合他克莫司软膏治疗玫瑰痤疮的临床效果良好，能有效缓解患者的临床 症状，改善皮肤屏障功能，且治疗后不良反应发生几率较小。
Objective To analyze the clinical efficacy of intensive pulsed light combined with tacrolimus ointment in the treatment of rosacea. Methods A total of 105 patients with rosacea who were treated in our hospital from October 2021 to December 2022 were selected as the research objects. According to the random number table method, they were divided into group A, group B and group C, with 35 patients in each group. Group A was treated with intensive pulsed light, group B was treated with tacrolimus ointment, and group C was treated with intensive pulsed light combined with tacrolimus ointment. The clinical efficacy, skin barrier function and adverse reactions of the three groups were compared. Results The total effective rate of treatment in group C was higher than that in group A and group B (P
赵 玲.强脉冲光联合他克莫司软膏治疗玫瑰痤疮的临床效果[J].医学美学美容,2023,32(14):50-53.
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