At present, burns, pressure sores and radioactive ulcers are the problems of wound repair. Although the drainage, skin grafting and flap repair have certain therapeutic effects, they cannot meet the appearance requirements of patients. Fat particle transplantation can achieve good plastic and cosmetic effects by extracting the patient's own subcutaneous fat, obtaining the required fat particle tissue after suction purification, and injecting it into the required parts of the body. However, there are differences in the application effect and application scope for different forms of fat microparticles transplantation. This article mainly analyzes the application progress on different forms of fat microparticles in wound repair, in order to provide more choices for improving skin wound repair.