In order to observe the efficacy and safety of OGP radiofrequency skin therapy device (medical 03) in the treatment of facial skin wrinkles and relaxation, this study selected 33 patients who underwent facial rejuvenation treatment in Xi’an Cunji Medical Center, University of Chinese Academy of Sciences from May to December 2022. The patients were treated with radiofrequency skin therapy device (medical 03) three times a week for 8 weeks, and the efficacy and degree of satisfaction were followed up before treatment, 4 weeks and 8 weeks. The evaluation included clinicians ' blind score, patient satisfaction survey and Primos. The results showed that 31 participants completed the study; two of them withdrew for personal reasons. The average value of Fitzpatrick wrinkle grade decreased after 56 days of using household radiofrequency skin therapy device (medical 03) (P