Objective To explore the clinical value of orthodontic treatment before oral repair. Methods From April 2021 to December 2022, 90 patients with dentition defect or malocclusion who needed oral repair in our hospital were selected as the research objects. They were randomly divided into control group and observation group, with 45 patients in each group. The control group was treated with routine oral repair, and the observation group was treated with orthodontic treatment before oral repair. The clinical efficacy, oral function, orthodontic effect, quality of life, plaque index, gingival sulcus bleeding index and complication rate were compared between the two groups. Results The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). The scores of language function, fixation function and chewing function in the observation group were higher than those in the control group, and the differences were statistically significant(P<0.05). The scores of anterior teeth arrangement, posterior teeth arrangement, occlusal relationship, overbite and overjet in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). The scores of functional limitation, physiological disorder, physiological pain, disability, psychological communication, social disorder and psychological obstruction in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). The gingival plaque index and gingival bleeding index in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). The incidence of complications in the observation group was lower than that in the control group, the difference was statistically significant (P<0.05). Conclusion The clinical effect of orthodontic treatment before oral repair is ideal, which can improve the oral function of patients, improve the level of oral health, reduce the breeding of dental plaque and gingival bleeding, and the incidence of complications is low.