Objective To analyze the effect of multiple skin expansion techniques in scar plastic surgery after head, face, and neck burns. Methods A total of 30 patients who underwent scar surgery after head, face, and neck burns in the 989th Hospital of Joint Logistics Support Force from January 2020 to September 2022 were selected as the study subjects. According to different treatment methods, they were divided into control group and observation group, with 15 patients in each group. The control group was treated with composite skin transplantation, and the observation group was treated with multiple skin expansion technique. The wound healing rate, clinical efficacy and complication rate were compared between the two groups. Results The wound healing rate of the observation group was higher than that of the control group on 2nd, 3rd and 4th weeks after operation (P<0.05). The total effective rate of treatment in the observation group was 93.33%, which was higher than 60.00% in the control group (P<0.05). The incidence of complications in the observation group was 6.67%, which was lower than 46.67% in the control group (P<0.05). Conclusion The application of multiple skin expansion technique in scar plastic surgery after head, face, and neck burns is effective, which can effectively improve the wound healing rate and relieve symptoms, and the incidence of postoperative complications is small and the safety is high.