To explore the effect of PPDO absorbable line biplane subcutaneous embedding in facial rejuvenation treatment. Methods Sixty patients with facial skin relaxation admitted to our hospital from January to December 2022 were randomly divided into control group and observation group, with 30 patients in each group. The control group was treated with PPDO serrated line single-plane subcutaneous embedding, and the observation group was treated with PPDO serrated line combined with PPDO spiral line biplane subcutaneous embedding. The adverse reactions of facial relaxation improvement were compared between the two groups. Results The excellent and good rate of facial relaxation improvement in the observation group was 96.67%, which was higher than 80.00% in the control group (P <0.05). The incidence and adverse reactions in the observation group was 3.33%, which was lower than 6.67% in the control group, but the difference was not statistically significant (P >0.05). Conclusion The application effect of PPDO absorbable suture biplane subcutaneous embedding in facial rejuvenation treatment is definite, which can effectively improve facial relaxation and enhance facial skin tightness. Meanwhile, it is conducive to improving facial aesthetics and achieving facial rejuvenation.