With the social and economic development, the progress of medical technology and the public's pursuit of a better life, the medical aesthetic industry is booming and requires a large number of high-quality medical aesthetic talents. This paper introduces the mode of clinical undergraduate medical and aesthetic talents training in Chengdu Medical Couege schools through institutional cooperation and innovative medical education. From the development of clinical medical aesthetic talents training program, to the construction of theoretical and practical teaching mode and the analysis and summary of the training effect of the first clinical undergraduate medical aesthetic class, it comprehensively introduces the initial training of clinical medical aesthetic talents in Chengdu Medical College, with a view to providing references for the undergraduate medical colleges to carry out the training of talents in the field of medical aesthetics.