季银焕（1977.10-），女，山东阳信县人，本科，副主任技师，主要从事医学检验工作
R758.24
目的 探讨血清总免疫球蛋白E（IgE）、特异性IgE（sIgE）、C反应蛋白（CRP）和白细胞介 素-6（IL-6）在急性荨麻疹诊断中的临床价值。方法 选取2022年6月-2023年4月我院收治的43例急性 荨麻疹患者纳入急性荨麻疹组，选取同期的43名健康者纳入对照组，检测两组血清总IgE、sIgE、CRP 及IL-6水平并进行比较。结果 急性荨麻疹组血清总IgE水平为（178.35±64.29）kU/L，高于对照组的 （86.42±30.57）kU/L，差异有统计学意义（P ＜0.05）；急性荨麻疹组户尘螨、食物过敏原、动物毛皮 屑、霉菌sIgE水平均高于对照组，差异有统计学意义（P ＜0.05）；急性荨麻疹组CRP、IL-6水平均高于 对照组，差异有统计学意义（P ＜0.05）。结论 血清总IgE、sIgE、CRP及IL-6在急性荨麻疹的诊断中具 有重要的临床价值，检测生物标志物有助于临床医生更准确地诊断急性荨麻疹，为患者提供更为精准的 治疗指导。
Objective To investigate the clinical value of serum total immunoglobulin E (IgE), specific IgE (sIgE), C-reactive protein (CRP) and interleukin-6 (IL-6) in the diagnosis of acute urticaria. Methods A total of 43 patients with acute urticaria admitted to our hospital from June 2022 to April 2023 were selected as the acute urticaria group, and 43 healthy members in the same period were selected as the control group. The levels of serum total IgE, sIgE, CRP and IL-6 were detected and compared between the two groups. Results The serum total IgE level in the acute urticaria group was (178.35±64.29) kU/L, which was higher than (86.42±30.57) kU/L in the control group, the difference was statistically significant (P <0.05). The levels of house dust mites, food allergens, animal dander, and mold sIgE in the acute urticaria group were higher than those in the control group, the difference was statistically significant (P <0.05). The levels of CRP and IL-6 in the acute urticaria group were higher than those in the control group, the difference was statistically significant (P <0.05). Conclusion Serum total IgE, sIgE, CRP and IL-6 have important clinical value in the diagnosis of acute urticaria. The detection of biomarkers is helpful for clinicians to diagnose acute urticaria more accurately and provide more accurate treatment guidance for patients.
季银焕. IL-6、CRP和血清过敏原检测对急性荨麻疹的临床价值[J].医学美学美容,2024,33(6):44-47.
复制
