The open practical teaching mode enhances students ' perceptual knowledge and practical ability by allowing students to participate in practical operation and combining theoretical knowledge with practice. This paper emphasizes the advantages of open practice teaching mode in improving students ' learning initiative, hands-on ability and professional potential, discusses the importance of promoting the integration of professional theoretical knowledge and practical operation skills, and puts forward some implementation strategies, such as scientifically dividing theory and practice teaching, reasonably optimizing and adjusting teaching design, balancing the learning differences of different students and increasing the application of information technology, in order to promote the reform and development of dermatology teaching, so as to cultivate more high-quality medical talents.