Objective To explore and analyze the therapeutic effect on sliding mode of narrow-spectrum delicate pulsed light combined with salicylic acid in the treatment of chloasma. Methods A total of 86 patients with chloasma who were treated in our hospital from January 2019 to September 2023 were selected as the research objects. They were divided into control group and experimental group by random number table method, with 43 patients in each group. The control group was treated with DPL sliding mode. The experimental group was treated with DPL sliding mode combined with salicylic acid. The mMASI score, physician global assesment and patient satisfaction of the two groups were compared and analyzed. Results After treatment, the mMASI score of the experimental group was (2.95±2.30) scores, which was lower than (3.72±2.24) scores of the control group (P <0.05). The physician global assesment in the experimental group was higher than that in the control group (P <0.05). The satisfaction of the experimental group was 93.35%, which was better than 81.40% of the control group (P <0.05). Conclusion For patients with chloasma, sliding mode of narrow-spectrum delicate pulsed light combined with salicylic acid treatment can reduce the mMASI score, improve the physician global assesment, and improve patient satisfaction.