Abstract:Objective To analyze the value of type A botulinum toxin+collagen injection in the treatment of facial wrinkles. Methods From November 2022 to November 2023, 76 patients with facial wrinkles admitted to Hangzhou Bellfield Medical Beauty Clinic were randomly divided into reference group and experimental group, with 38 patients in each group. The reference group was treated with type A botulinum toxin, and the experimental group was treated with collagen on the basis of the reference group. The skin indexes, clinical efficacy and satisfaction rate of the two groups were compared. Results The skin moisture and skin elasticity scores of the two groups after treatment were higher than those before treatment, and those of the experimental group were higher than those of the reference group (P <0.05). The effective rate of the experimental group was 100.00%, which was higher than 89.47% of the reference group (P <0.05). The satisfaction rate of the experimental group was 97.37%, which was higher than 81.58% of the reference group (P <0.05). Conclusion Type A botulinum toxin+collagen injection treatment has a good effect on facial wrinkles. It can not only improve skin moisture and elasticity, eliminate facial wrinkles, but also has a high patient satisfaction rate.