Objective To evaluate the success rate and safety of dental implantation using regenerated oral repair membrane and titanium membrane for guided bone regeneration in the treatment of alveolar bone defects. Methods A total of 68 patients with dental implant admitted to our hospital from May 2022 to December 2023 were selected as the research objects and randomly divided into reference group and experimental group, with 34 patients in each group. The reference group was treated with titanium membrane for guided bone regeneration, and the experimental group was treated with regenerated oral repair membrane for guided bone regeneration. The complications, repair success rate, repair satisfaction bone thickness and bone density were compared between the two groups. Results The incidence of complications in the experimental group was 5.88%, which was lower than 23.53% in the reference group (P <0.05). The repair success rate of the experimental group was 97.06 %, which was higher than 73.53% of the reference group (P <0.05). The repair satisfaction of the experimental group was 97.06%, which was higher than 79.41% of the reference group (P <0.05). The bone thickness and bone density of the bone graft area in the experimental group were higher than those in the reference group (P <0.05). Conclusion The use of regenerated oral repair membrane during dental implantation can effectively improve bone thickness and bone density, reduce the incidence of complications, and improve the success rate and satisfaction of repair.