米诺地尔治疗桥本氏甲状腺炎合并脱发1例
作者:
作者简介:

韩乐(1990.10-),男,宁夏银川人,硕士,住院医师,主要从事毛发疾病、皮肤肿瘤、皮肤外科疾病诊疗工作

通讯作者:

蒋雨辰(1993.1-),女,广东广州人,硕士,主治医师,主要从事皮肤科常见病及疑难病诊疗工作

中图分类号:

R581; R758.71


Patch Test Results of Patients with Dermatitis and Eczema in Suzhou Industrial Park
  • 摘要
  • | |
  • 访问统计
  • |
  • 参考文献 [14]
  • |
  • 相似文献 [20]
  • | | |
  • 文章评论
    摘要:

    目的 了解并分析苏州工业园区皮炎湿疹类皮肤病患者接触性变应原及其特点。方法 选择2021年 8月-2023年10月就诊于本院皮肤科门诊的102例皮炎湿疹类皮肤病患者为研究对象,采用斑贴试验诊断盒 分析患者的接触性变应原情况。结果 102例皮炎湿疹类皮肤病患者中,斑贴试验阳性率为43.13%,阳性率 由高至低依次为硫酸镍(21.57%)、氯化钴(16.67%)、重铬酸钾(15.69%)、氯化镍(13.73%),脂肪酸 硫酸钠(13.73%)等;男女患者的斑贴试验阳性率比较,差异无统计学意义(P >0.05)。结论 硫酸镍、 氯化钴、重铬酸钾、氯化镍、脂肪酸硫酸钠是苏州工业园区皮炎湿疹类患者的主要接触性致敏原。

    Abstract:

    Objective To understand and analyze the contact allergens and their characteristics in patients with dermatitis and eczema in Suzhou Industrial Park. Methods A total of 102 patients with dermatitis and eczema skin diseases who were treated in the dermatology clinic of our hospital from August 2021 to October 2023 were selected as the research objects. The patch test diagnostic box was used to analyze the contact allergens of the patients. Results Among 102 patients with dermatitis and eczema, the positive rate of patch test was 43.13%. The positive rate from high to low was nickel sulfate (21.57%), cobalt chloride (16.67%), potassium dichromate (15.69%), nickel chloride (13.73%), fatty acid sodium sulfate (13.73%), etc. There was no significant difference in the positive rate of patch test between male and female patients (P >0.05). Conclusion Nickel sulfate, cobalt chloride, potassium dichromate, nickel chloride and fatty acid sodium sulfate are the main contact allergens in patients with dermatitis and eczema in Suzhou Industrial Park.

    参考文献
    [1]Zhang X,Wang X,Hu H,et al.Prevalence and trends of thyroid disease among adults,1999-2018[J].Endocr pract,2023,29(11):875-880.
    [2]Hussein RS,Atia T,Bin Dayel S.Impact of thyroid dysfunction on hair disorders[J].Cureus,2023,15(8):e43266.
    [3]Aboalola D,Aouabdi S,Ramadan M,et al.An update on alopecia and its association with thyroid autoimmune diseases[J].TouchREV Endocrinol,2023,19(2):54-59.
    [4]Naik PP,Farrukh SN.Association between alopecia areata and thyroid dysfunction[J].Postgrad Med,2021,133(8):895- 898.
    [5]Lee S,Lee YB,Kim BJ,et al.Screening of thyroid function and autoantibodies in patients with alopecia areata: a systematic review and meta-analysis[J].J Am Acad Dermatol,2019,80(5):1410-1413.
    [6]Moseley IH,Thompson JM,George EA,et al.Immunemediated diseases and subsequent risk of alopecia areata in a prospective study of US women[J].Arch Dermatol Res,2023,315(4):807-813.
    [7]Naik PP,Farrukh SN.Association between alopecia areata and thyroid dysfunction[J].Postgrad Med,2021,133(8):895- 898.
    [8]Bogus?awska J,Godlewska M,Gajda E,et al.Cellular and molecular basis of thyroid autoimmunity[J].Eur Thyroid J,2022,11(1):e210024.
    [9]Seok J,Cho SD,Lee J,et al.A virtual memory CD8+ T celloriginated subset causes alopecia areata through innatelike cytotoxicity[J].Nat Immunol,2023,24(8):1308-1317.
    [10]Rajabi F,Drake LA,Senna MM,et al.Alopecia areata: a review of disease pathogenesis[J].Br J Dermatol, 2018,179(5):1033-1048.
    [11]Wan S,Xu W,Xie B,et al.The potential of regulatory T cell-based therapies for alopecia areata[J].Front Immunol, 2023,14:1111547.
    [12]Popa A,Carsote M,Cretoiu D,et al.Study of the thyroid profile of patients with alopecia[J].J Clin,2023,12(3):1115.
    [13]Asghar F,Shamim N,Farooque U,et al.Telogen effluvium: a review of the literature[J].Cureus,2020,12(5):e8320.
    [14]Zhang QY,Ye XP,Zhou Z,et al.Lymphocyte infiltration and thyrocyte destruction are driven by stromal and immune cell components in Hashimoto’s thyroiditis[J].Nat Commun,2022,13(1):775.
    引证文献
    网友评论
    网友评论
    分享到微博
    发 布
引用本文

韩乐,蒋雨辰.米诺地尔治疗桥本氏甲状腺炎合并脱发1例[J].医学美学美容,2024,33(9):144-146.

复制
分享
文章指标
  • 点击次数:54
  • 下载次数: 0
  • HTML阅读次数: 0
  • 引用次数: 0
历史
  • 在线发布日期: 2024-05-13