Objective To explore the effect of psychological nursing on patients with oral and maxillofacial fractures and its influence on their psychological state, quality of life and facial aesthetics. Methods A total of 102 patients with oral and maxillofacial fractures admitted to our hospital from January 2022 to December 2023 were selected as the research objects. According to the random number table method, they were divided into control group and observation group, with 51 patients in each group. The control group was given routine nursing, and the observation group was given psychological nursing on the basis of the control group. The psychological state, quality of life, facial beauty and nursing satisfaction were compared between the two groups. Results After intervention, the SAS score and SDS score of the observation group were lower than those of the control group (P <0.05). After intervention, the scores of all dimensions of quality of life in the observation group were higher than those in the control group (P <0.05). After intervention, the PES score of the observation group was higher than that of the control group (P <0.05). The nursing satisfaction rate of the observation group was 98.04%, which was higher than 86.27% of the control group (P <0.05). Conclusion For patients with oral and maxillofacial fractures, psychological nursing can effectively improve their negative emotions, improve the facial aesthetics and quality of life, and patients' satisfaction is high.