Objective To investigate the clinical value of microscrew implant in the correction of class Ⅱ malocclusion. Methods From December 2022 to December 2023, 100 patients with class Ⅱ malocclusion received by Zhang Shaoshan Stomatological Clinic in Yanta District of Xi'an City were selected. The patients received from December 2022 to May 2023 were set as group A, and the patients received from June to December 2023 were set as group B, with 50 patients in each group. Group A was treated with traditional orthodontic treatment, and group B was treated with microscrew implant anchorage. The jaw and tooth-related indicators, inflammation indexes and complication rates were compared between the two groups. Results The upper alveolar seat angle, the lower alveolar seat angle, the upper and lower alveolar seat angle, the jaw plane angle, the angle between the long axis of the upper central incisor and the SN plane, and the vertical distance from the cutting edge of the upper central incisor to the upper alveolar seat point in group B were better than those in group A (P <0.05). The levels of IL-6 and IL-8 in group B were lower than those in group A (P <0.05). The incidence of complications in group B was 4.00%, which was lower than 26.00 % in group A (P <0.05). Conclusion Microscrew implant treatment for patients with Class Ⅱ malocclusion can effectively improve the clinical indicators of patients and has higher clinical application value.