Objective: To explore the clinical similarities and differences between mini-implant anchorage and traditional orthodontics. Methods: A practical study was conducted on 64 patients receiving orthodontic treatment from May 2021 to May 2025. Grouping was performed using a lottery method to ensure equal sample sizes, with 32 cases in each group. The control group received conventional orthodontic treatment, while the study group used mini-implant anchorage orthodontic technology. Chewing efficiency and aesthetics, X-ray measurement indicators, and the incidence of adverse reactions were statistically analyzed for both groups. Results: (1) After treatment, the study group showed higher chewing efficiency and aesthetic outcomes compared to the control group (P<0.05). (2) Post-treatment, the study group had lower values for alveolar ridge angle and molar displacement compared to the control group, while the upper central incisor tilt angle and inter-canine width were higher than in the control group (P<0.05). (3) The incidence of adverse reactions in the study group was lower than in the control group (P<0.05). Conclusion: In clinical orthodontic treatment, mini-implant anchorage provides better aesthetics and chewing function than traditional orthodontics, while also promoting recovery of oral imaging indicators and reducing the risk of adverse reactions. 【Keywords】Orthodontic treatment; Mini-implant anchorage; Traditional orthodontics; Adverse reactions