Objective To analyze the effect of standardized nursing intervention on scar repair effect in children undergoing general surgery. Methods A total of 60 children who underwent general surgery and were admitted to the Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology from February 2022 to April 2025 were selected as the research subjects, and they were divided into the control group and the observation group by random number table method, with 30 children in each group. The control group received conventional nursing, and the observation group received standardized nursing intervention. The incision healing time, scar repair effect, nursing satisfaction and adverse reaction rate were compared between the two groups. Results The incision healing time of the observation group was shorter than that of the control group (P <0.05). The VSS score of the observation group after nursing was lower than that of the control group (P <0.05). The nursing satisfaction rate of the observation group (96.67%) was better than that of the control group (76.67%) (P <0.05). The incidence of adverse reactions in the observation group (6.67%) was lower than that in the control group (30.00%) (P <0.05). Conclusion In general surgery, the application of standardized nursing mode for children can effectively promote incision healing, improve scar repair effect, and reduce the risk of adverse reactions. This mode not only improves the overall satisfaction of children, but also shows important clinical application value.