Objective: To analyze the nursing effect of digital guide plate-assisted oral implant restoration in patients with dentition defect and the influence of this measure on the aesthetic degree of the restoration. Methods: 100 patients with dentition defect who were admitted to our hospital"s oral department from January 2023 to December 2025 were selected. Using the random number table method, the patients were divided into the observation group and the control group, with 50 cases in each group. The control group received traditional oral implant restoration treatment, while the observation group received digital guide plate-assisted oral implant restoration treatment. The surgical indicators related to implantation, chewing function, periodontal health indicators, and restoration aesthetic score of the two groups were compared. Results: The operation time of the observation group was shorter than that of the control group, the intraoperative bleeding volume was less than that of the control group, and the accuracy rate of implant implantation was higher than that of the control group (P < 0.05). After the intervention, the bite force and chewing efficiency of the observation group were higher than those of the control group (P < 0.05), and the periodontal health indicators of the observation group were better than those of the control group (P < 0.05). The aesthetic score of the restoration of the observation group was higher than that of the control group (P < 0.05). Conclusion: The application of digital guide plate-assisted oral implant restoration in patients with dentition defect can reduce the operation time and intraoperative bleeding, improve the implant implantation accuracy, and improve the chewing function and periodontal health of patients, and significantly improve the aesthetic degree of the restoration.