Periodontal disease has a high incidence rate among people of all ages. The disease types include periodontitis and gingivitis. The causes include local oral problems, unhealthy lifestyles, and systemic diseases, which can have a significant impact on the appearance of teeth. Periodontal disease sequence treatment is a systematic treatment plan for periodontal disease, which can control infection, alleviate inflammatory reactions, and improve periodontal health. Using only periodontal disease sequence treatment is difficult to meet patients" requirements for dental cosmetic effects. Oral medical aesthetic treatment and oral medical aesthetic reconstruction plans can improve the appearance of teeth and solve the shortcomings of single periodontal disease sequence treatment. The research plan summarizes the clinical progress of periodontal disease cosmetic treatment and oral medical aesthetic reconstruction, with the aim of providing reference for clinical research.