Objective To analyze the effect of digital guide plate-guided oral implant restoration on restoration aesthetics in patients with dentition defect. Methods A total of 100 patients with dentition defect treated at Kundulun District FAN Lijun Dental Clinic from January 2023 to May 2025 were selected as the research subjects. According to the random number table method, they were divided into group A and group B, with 50 patients in each group. Group A received conventional implant restoration, and group B received digital guide plate-guided oral implant restoration. The operation related indicators, periodontal health indicators and restoration aesthetics were compared between the two groups. Results The operation duration and intraoperative blood loss of group B were better than those of group A, and the implant success rate was higher than that of group A (P<0.05). After intervention, the GI, PD and AL in group B were lower than those in group A (P<0.05). The scores of shape coordination, color matching, tooth alignment and overall aesthetics in group B were better than those in group A (P<0.05). Conclusion For patients with dentition defect, the application of digital guide plate-guided oral implant restoration can effectively improve implant success rate and restoration aesthetics, and help to improve periodontal health, reduce operation time and intraoperative blood loss.