强脉冲光联合透明质酸注射对面部细纹患者皮肤弹性 及毛孔粗大程度的改善作用
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姜筱唐(1988.4-),女,黑龙江齐齐哈尔人,硕士,主治医师,主要从事整形美容外科方面工作

通讯作者:

续言凤(1984.8-),女,山东泰安人,硕士,副主任医师,主要从事皮肤科方面工作

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R622

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Improvement Effect of Intense Pulsed Light Combined with Hyaluronic Acid Injection on Skin Elasticity and Pore Enlargement in Patients with Facial Fine Lines
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    摘要:

    目的 探究强脉冲光(IPL)联合透明质酸(HA)注射改善面部细纹患者皮肤弹性、毛孔粗大程 度的作用。方法 选取2022年1月-2025年12月于航空总医院就诊的60例面部细纹患者,采用随机数字表法 分为对照组与观察组,各30例。对照组行单纯IPL治疗,观察组在对照组基础上联合HA注射,比较两组皮 肤弹性、毛孔粗大程度、皮肤屏障功能及真皮结构与细纹参数。结果 两组治疗后R2、R5、R7均高于治疗 前,且观察组高于对照组(P <0.05);两组治疗后毛孔面积百分比、毛孔计数及平均毛孔直径均低于治疗 前,且观察组低于对照组(P<0.05);两组治疗后TEWL低于治疗前,且观察组低于对照组(P <0.05); 两组治疗后角质层含水量与皮脂含量均高于治疗前,且观察组高于对照组(P<0.05);两组治疗后真皮厚 度及皮肤光泽度均高于治疗前,且观察组高于对照组(P <0.05);两组治疗后细纹面积百分比均低于治疗 前,且观察组低于对照组(P<0.05)。结论 IPL联合HA注射能协同提升面部细纹患者皮肤弹性、缩小毛 孔,有效修复皮肤屏障功能,增厚真皮结构,淡化细纹,整体疗效优于单纯IPL治疗。

    Abstract:

    Objective To investigate the improvement effect of intense pulsed light (IPL) combined with hyaluronic acid (HA) injection on skin elasticity and pore enlargement in patients with facial fine lines. Methods A total of 60 patients with facial fine lines admitted to Aviation General Hospital from January 2022 to December 2025 were selected, and they were divided into the control group and the observation group by the random number table method, with 30 patients in each group. The control group received IPL monotherapy, and the observation group received additional HA injection on the basis of the control group. The skin elasticity, pore enlargement, skin barrier function, dermal structure and fine line parameters were compared between the two groups. Results After treatment, the R2, R5, and R7 values in the two groups were higher than those before treatment, and those in the observation group were higher than those in the control group (P <0.05). After treatment, the percentage of pore area, pore count and mean pore diameter in the two groups were lower than those before treatment, and those in the observation group were lower than those in the control group (P <0.05). After treatment, the TEWL in the two groups was lower than that before treatment, and that in the observation group was lower than that in the control group (P <0.05). After treatment, the stratum corneum hydration and sebum content in the two groups were higher than those before treatment, and those in the observation group were higher than those in the control group (P <0.05). After treatment, the dermal thickness and skin gloss in the two groups were higher than those beforetreatment, and those in the observation group were higher than those in the control group (P <0.05). After treatment, the percentage of fine line area in the two groups was lower than that before treatment, and that in the observation group was lower than that in the control group (P <0.05). Conclusion The combination of IPL and HA injection can synergistically improve skin elasticity and reduce pore size in patients with facial fine lines, effectively repair skin barrier function, thicken the dermal structure, and reduce the appearance of fine lines. The overall therapeutic efficacy is superior to that of IPL monotherapy.

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姜筱唐,续言凤.强脉冲光联合透明质酸注射对面部细纹患者皮肤弹性 及毛孔粗大程度的改善作用[J].医学美学美容,2026,35(15):27-31.

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  • 在线发布日期: 2026-09-22
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