Anchorage control is the core link of orthodontic treatment. Although conventional anchorage methods such as extraoral arch and transpalatal arch can enhance anchorage to a certain extent, they usually depend on patient compliance and cannot provide genuine “absolute anchorage”. Temporary Anchorage Devices (TADs) have become an important anchorage modality in modern orthodontics owing to their small size and flexible insertion. Nevertheless, clinical stability remains a key factor restricting treatment effects. Starting from the basic concept of TADs-related stability, this paper systematically summarizes major influencing factors, including patient factors, mini-implant design and materials, insertion procedures, loading conditions and cortical bone micro-damage. It also briefly reviews its clinical application progress in molar distalization, anterior teeth retraction and molar intrusion, so as to provide references for rational clinical application of TADs and further improvement of their stability.